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KMID : 1012420160250030109
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Korean Journal of Obesity
2016 Volume.25 No. 3 p.109 ~ p.114
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Food Intake and Thermogenesis in Adipose Tissue
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Goto Tsuyoshi
Kim Min-Ji
Takahashi Haruya
Takahashi Nobuyuki
Kawada Teruo
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Abstract
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Brown adipose tissue (BAT) is regarded as a key target for developing interventions to prevent and treat obesity and age-related diseases. In addition, uncoupling pro tein 1 (UCP1) - expressing “brown-like” adipocytes, known as beige cells, that develop in white adipose tissue (WAT) under certain physiological conditions and pharmacological stimuli. The effects of ageing on BAT atrophy and functional decline further strengthen the notion that healthy eating habits and food choices play an extremely vital role against reduction in the number of BAT and beige cells as people approach middle age. This review aims to cover recent progress in food items and pharmaceuticals that activate or induce BAT and UCP1.
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KEYWORD
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Food components, Obesity, Brown adipose tissue, Uncoupling protein, Beige cells, Transient receptor potential (TRP) channels
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